Isle of Dogs is a 2018 adult stop-motion animated science fiction comedy-drama film written, produced, and directed by Wes Anderson, narrated by Courtney B. Vance, and starring an ensemble cast that consists of Bryan Cranston, Koyu Rankin, Edward Norton, Liev Schreiber, Bill Murray, Bob Balaban, Jeff Goldblum, Scarlett Johansson, Kunichi Nomura, Tilda Swinton, Ken Watanabe, Akira Ito, Greta Gerwig, Akira Takayama, Frances McDormand, F. Murray Abraham, Yojiro Noda, Fisher Stevens, Mari Natsuki, Nijiro Murakami, Yoko Ono, Harvey Keitel, and Frank Wood. An American-German-British co-production, Isle of Dogs was produced by Studio Babelsberg and Indian Paintbrush in association with Anderson's own company American Empirical Pictures. This was Anderson's second stop-motion film, following Fantastic Mr. Fox. The film is set in the fictional Japanese city of Megasaki where Mayor Kenji Kobayashi has banished all dogs to Trash Island due to a canine influenza pandemic. Kobayashi's nephew Atari sets out to find his missing dog Spots with the help of a group of dogs led by stray dog Chief.